Advances in Diabetes & Endocrinology

Case Report

Management of Hyperglycemic Hyperosmolar State with Hyperension

Sibi Das*

Department of Medicine, NC Medical College, Israna, Panipat, Haryana, India.
*Address for Correspondence:Dr. Sibi Das, Department of Medicine, NC Medical College, Israna, Panipat, Haryana, India. E-mail Id: sdsilvanose@gmail.com
Submission:27 January, 2026 Accepted:24 February, 2026 Published: 26 February, 2026
Copyright: © 2026 Das S This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Management of Hyperosmolar Hyperglycemic State (HHS) with coexisting hypertension is a medical emergency requiring urgent, multidisciplinary care and immediate hospitalization. Treatment focuses on aggressive intravenous fluid resuscitation, careful electrolyte replacement—particularly potassium—and lowdose insulin therapy to gradually reduce hyperglycemia while minimizing the risk of cerebral edema. Concurrently, underlying precipitating factors, most commonly infection, must be identified and treated. Preventive measures against complications such as thromboembolism, including prophylactic heparin, are also essential in the absence of hemorrhagic stroke.