Advances in Diabetes & Endocrinology
Case Report
Management of Hyperglycemic Hyperosmolar State with Hyperension
Sibi Das*
Department of Medicine, NC Medical College, Israna, Panipat, Haryana, India.
*Address for Correspondence:Dr. Sibi Das, Department of Medicine, NC Medical College,
Israna, Panipat, Haryana, India. E-mail Id: sdsilvanose@gmail.com
Submission:27 January, 2026
Accepted:24 February, 2026
Published: 26 February, 2026
Copyright: © 2026 Das S This is an open access article
distributed under the Creative Commons Attribution License,
which permits unrestricted use, distribution, and reproduction
in any medium, provided the original work is properly cited.
Abstract
Management of Hyperosmolar Hyperglycemic State (HHS) with coexisting
hypertension is a medical emergency requiring urgent, multidisciplinary care
and immediate hospitalization. Treatment focuses on aggressive intravenous fluid
resuscitation, careful electrolyte replacement—particularly potassium—and lowdose
insulin therapy to gradually reduce hyperglycemia while minimizing the risk
of cerebral edema. Concurrently, underlying precipitating factors, most commonly
infection, must be identified and treated. Preventive measures against complications
such as thromboembolism, including prophylactic heparin, are also essential in the
absence of hemorrhagic stroke.
