Journal of Pediatrics & Child Care

Case Report

Use of Formoterol Fumarate for Bronchodilator Reversibility Testing in the Paediatric Population

Khan HS*, Quinn C, Kirshan S and Louka E

Department of Pediatrics, Hull University Teaching Hospitals NHS
*Address for Correspondence:Haji Sheeraz Khan, Department of Pediatrics, Hull University Teaching Hospitals NHS E-mail Id: Hkhan2@nhs.net
Submission: 10 June, 2025 Accepted: 30 June, 2025 Published: 04 July, 2025
Copyright: © 2025 Khan HS, et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Keywords:Formoterol Fumarate; Bronchodilator Reversibility; BDR; Asthma; Paediatrics; LABA; Symbicort

Abstract

Bronchodilator reversibility (BDR) testing is a vital tool in the objective diagnosis of paediatric asthma, as per current BTS, NICE, and SIGN guidelines. Salbutamol, a short-acting beta2 agonist (SABA), is typically used. However, we present a clinical case where Formoterol Fumarate, a fast-acting long-acting beta agonist (LABA), was successfully employed for BDR testing in a child with intolerance to Salbutamol. To our knowledge this is first case report of a 10 years old child where Budesonide/Formoterol was used for BDR. A 9% improvement in FEV1 was observed following the use of Symbicort Turbohaler® (Budesonide/Formoterol), closely approaching the 10% threshold for positive reversibility. Although evidence in children is limited, our case supports the consideration of Formoterol in select scenarios, particularly when adverse reactions to SABA therapies limit diagnostic assessment and also for those children who are on exclusively Budesonide/Formoterol (MART or AIR therapy).