Journal of Pediatrics & Child Care
Case Report
Use of Formoterol Fumarate for Bronchodilator Reversibility Testing in the Paediatric Population
Khan HS*, Quinn C, Kirshan S and Louka E
Department of Pediatrics, Hull University Teaching Hospitals NHS
*Address for Correspondence:Haji Sheeraz Khan, Department of Pediatrics, Hull
University Teaching Hospitals NHS E-mail Id: Hkhan2@nhs.net
Submission: 10 June, 2025
Accepted: 30 June, 2025
Published: 04 July, 2025
Copyright: © 2025 Khan HS, et al. This is an open access
article distributed under the Creative Commons Attribution
License, which permits unrestricted use, distribution, and
reproduction in any medium, provided the original work is
properly cited.
Keywords:Formoterol Fumarate; Bronchodilator Reversibility; BDR;
Asthma; Paediatrics; LABA; Symbicort
Abstract
Bronchodilator reversibility (BDR) testing is a vital tool in the
objective diagnosis of paediatric asthma, as per current BTS, NICE,
and SIGN guidelines. Salbutamol, a short-acting beta2 agonist
(SABA), is typically used. However, we present a clinical case where
Formoterol Fumarate, a fast-acting long-acting beta agonist (LABA),
was successfully employed for BDR testing in a child with intolerance
to Salbutamol. To our knowledge this is first case report of a 10 years
old child where Budesonide/Formoterol was used for BDR. A 9%
improvement in FEV1 was observed following the use of Symbicort
Turbohaler® (Budesonide/Formoterol), closely approaching the 10%
threshold for positive reversibility. Although evidence in children is
limited, our case supports the consideration of Formoterol in select
scenarios, particularly when adverse reactions to SABA therapies
limit diagnostic assessment and also for those children who are on
exclusively Budesonide/Formoterol (MART or AIR therapy).