Alzheimers Disease is the most frequent form of dementia, the condition is identify the problems with thinking and memory, as well as changes in behavior and mood, thesr are very severe over the time. Researches declare how a advanced, high resolution imaging technique is used to identify the Alzheimers Diasease (AD) patients beta-amyloid plaques in retinas.
The precise reason of Alzheimers is ongoing, scientists know that the condition is involved in the degradation and death of brain cells.The bêta-amyloid is considered a key infractor in this process.
About beta-amyloid pretein:
Beta-amyloid is a sticky particle of the amyloid precursor protein, it occupy in the fatty tissue surrounding brain cells and neurons. In this disease beta-amyloid particles are assembly together and form plaques in the brain that damage the neuronal communication and activate the immune cell. It leads swelling to the brain cell death. Healthcare professionals use positron emission tomography of CF (Cerebro Fluid ) analysis to observe the beta-amyloid and make an Alzheimer’s diagnosis.
Recent studies are shown that beta-amyloid can be detected in the retina, it is light-sensitive tissue lines in the back of the eye and it pass the signals to the brain. The scientists are used retinal imaging technique for recognise beta-amyloid deposits and diagnosing AD.
Identify the beta-amyloid in the retina: The retinal imaging technique is identified a 4.7 times greater abundance of beta-amyloid plaques in the retinas of the patients with AD, compared with the retinas of the controls. The researchers tested imaging method on retinas of 23 deceased AD patients along with 14 age matched persons who did not have AD. In that they identify higher plaques in the retina of AD patients than controls. The beta-amyloid plaques are correlated with the neuronal loss in the AD patients brains. Finally this technique is a reasonable, low cost screening test fot the diagnosis of AD.